morally reprehensible; "would do something as despicable as murder"; "ugly crimes"; "the vile development of slavery appalled them"; "a slimy little liar"
characterized by physical misery; "a wet miserable weekend"; "spent a wretched night on the floor"
very unhappy; full of misery; "he felt depressed and miserable"; "a message of hope for suffering humanity"; "wretched prisoners huddled in stinking cages"