something that causes or entails suffering; "I cannot think it a hardship that more indulgence is allowed to men than to women"- James Boswell; "the many hardships of frontier life"
mutability in life or nature (especially successive alternation from one condition to another)
a variation in circumstances or fortune at different times in your life or in the development of something; "the project was subject to the usual vicissitudes of exploratory research"
a life preserver consisting of a connected pair of inflatable bags that fit under a person's arms and provide buoyancy; used by children learning to swim
special and significant stress by means of position or repetition e.g.
special importance or significance; "the red light gave the central figure increased emphasis"; "the room was decorated in shades of grey with distinctive red accents"
something or someone that causes trouble; a source of unhappiness; "washing dishes was a nuisance before we got a dish washer"; "a bit of a bother"; "he's not a friend, he's an infliction"