a surrounding or nearby region; "the plane crashed in the vicinity of Asheville"; "it is a rugged locality"; "he always blames someone else in the immediate neighborhood"; "I will drop in on you the next time I am in this neck of the woods"
something that causes or entails suffering; "I cannot think it a hardship that more indulgence is allowed to men than to women"- James Boswell; "the many hardships of frontier life"
mutability in life or nature (especially successive alternation from one condition to another)
a variation in circumstances or fortune at different times in your life or in the development of something; "the project was subject to the usual vicissitudes of exploratory research"
not ever; at no time in the past or future; "I have never been to China"; "I shall never forget this day"; "had never seen a circus"; "never on Sunday"; "I will never marry you!"
not at all; certainly not; not in any circumstances; "never fear"; "bringing up children is never easy"; "that will never do"; "what is morally wrong can never be politically right"
emptied or exhausted of (as by drawing off e.g. water or other liquid); "a drained marsh"; "a drained tank"; "a drained and apathetic old man...not caring any longer about anything"