excite to an abnormal condition, of chafe or inflame; "Aspirin irritates my stomach"
excite to some characteristic action or condition, such as motion, contraction, or nervous impulse, by the application of a stimulus; "irritate the glands of a leaf"
thrown into a state of intense fear or desperation; "became panicky as the snow deepened"; "felt panicked before each exam"; "trying to keep back the panic-stricken crowd"; "the terrified horse bolted"