something or someone that causes trouble; a source of unhappiness; "washing dishes was a nuisance before we got a dish washer"; "a bit of a bother"; "he's not a friend, he's an infliction"
the state of being emotionally aroused and worked up; "his face was flushed with excitement and his hands trembled"; "he tried to calm those who were in a state of extreme inflammation"
excite to an abnormal condition, of chafe or inflame; "Aspirin irritates my stomach"
excite to some characteristic action or condition, such as motion, contraction, or nervous impulse, by the application of a stimulus; "irritate the glands of a leaf"