backache affecting the lumbar region or lower back; can be caused by muscle strain or arthritis or vascular insufficiency or a ruptured intervertebral disc
any large scale calamity (especially when thought to be sent by God)
any epidemic disease with a high death rate
a serious (sometimes fatal) infection of rodents caused by Yersinia pestis and accidentally transmitted to humans by the bite of a flea that has bitten an infected animal
marked by immorality; deviating from what is considered right or proper or good; "depraved criminals"; "a perverted sense of loyalty"; "the reprobate conduct of a gambling aristocrat"
completely lacking nobility in character or quality or purpose; "something cowardly and ignoble in his attitude"; "I think it a less evil that some criminals should escape than that the government should play an ignoble part"- Oliver Wendell Holmes, Jr.
not of the nobility; "of ignoble (or ungentle) birth"; "untitled civilians"
the occurrence of incoming water (between a low tide and the following high tide); "a tide in the affairs of men which, taken at the flood, leads on to fortune" -Shakespeare
harsh or severe speech or behavior; "men associate the roughness of nonstandard working-class speech with masculinity"; "the roughness of her voice was a signal to keep quiet"
a texture of a surface or edge that is not smooth but is irregular and uneven