characterized by physical misery; "a wet miserable weekend"; "spent a wretched night on the floor"
very unhappy; full of misery; "he felt depressed and miserable"; "a message of hope for suffering humanity"; "wretched prisoners huddled in stinking cages"
an unexpected and inexplicable change in something (in a situation or a person's behavior, etc.); "the vagaries of the weather"; "his wealth fluctuates with the vagaries of the stock market"; "he has dealt with human vagaries for many years"