something inverted in sequence or character or effect; "when the direct approach failed he tried the inverse"
reversed (turned backward) in order or nature or effect
opposite in nature or effect or relation to another quantity ; "a term is in inverse proportion to another term if it increases (or decreases) as the other decreases (or increases)"
something that causes or entails suffering; "I cannot think it a hardship that more indulgence is allowed to men than to women"- James Boswell; "the many hardships of frontier life"
mutability in life or nature (especially successive alternation from one condition to another)
a variation in circumstances or fortune at different times in your life or in the development of something; "the project was subject to the usual vicissitudes of exploratory research"