not easily borne; wearing; "the burdensome task of preparing the income tax return"; "my duties weren't onerous; I only had to greet the guests"; "a taxing schedule"
mutability in life or nature (especially successive alternation from one condition to another)
a variation in circumstances or fortune at different times in your life or in the development of something; "the project was subject to the usual vicissitudes of exploratory research"
existing for a long time; "hopes for a durable peace"; "a long-lasting friendship"
very long lasting; "less durable rocks were gradually worn away to form valleys"; "the perdurable granite of the ancient Appalachian spine of the continent"
serviceable for a long time; "durable denim jeans"
(pharmacology) a book containing a compilation of pharmaceutical products with their formulas and methods of preparation; "postexposure prophylaxis is an integral part of the pharmacopeia in preventing severe disease after acute infections"
difficult to penetrate; incomprehensible to one of ordinary understanding or knowledge; "the professor's lectures were so abstruse that students tended to avoid them"; "a deep metaphysical theory"; "some recondite problem in historiography"
requiring more than usually expected or thought due; especially great patience and effort and skill; "found the job very demanding"; "a baby can be so demanding"