backache affecting the lumbar region or lower back; can be caused by muscle strain or arthritis or vascular insufficiency or a ruptured intervertebral disc
any large scale calamity (especially when thought to be sent by God)
any epidemic disease with a high death rate
a serious (sometimes fatal) infection of rodents caused by Yersinia pestis and accidentally transmitted to humans by the bite of a flea that has bitten an infected animal
marked by immorality; deviating from what is considered right or proper or good; "depraved criminals"; "a perverted sense of loyalty"; "the reprobate conduct of a gambling aristocrat"
completely lacking nobility in character or quality or purpose; "something cowardly and ignoble in his attitude"; "I think it a less evil that some criminals should escape than that the government should play an ignoble part"- Oliver Wendell Holmes, Jr.
not of the nobility; "of ignoble (or ungentle) birth"; "untitled civilians"