make (alcohol) unfit for drinking without impairing usefulness for other purposes
modify (as a native protein) especially by heat, acid, alkali, or ultraviolet radiation so that all of the original properties are removed or diminished
add nonfissionable material to (fissionable material) so as to make unsuitable for use in an atomic bomb
thrown into a state of intense fear or desperation; "became panicky as the snow deepened"; "felt panicked before each exam"; "trying to keep back the panic-stricken crowd"; "the terrified horse bolted"