something or someone that causes trouble; a source of unhappiness; "washing dishes was a nuisance before we got a dish washer"; "a bit of a bother"; "he's not a friend, he's an infliction"
an abusive attack on a person's character or good name
a disparaging remark; "in the 19th century any reference to female sexuality was considered a vile aspersion"; "it is difficult for a woman to understand a man's sensitivity to any slur on his virility"