(genetics) a segment of DNA that is involved in producing a polypeptide chain; it can include regions preceding and following the coding DNA as well as introns between the exons; it is considered a unit of heredity; "genes were formerly called factors"
any of the more than 100 known substances (of which 92 occur naturally) that cannot be separated into simpler substances and that singly or in combination constitute all matter
requiring more than usually expected or thought due; especially great patience and effort and skill; "found the job very demanding"; "a baby can be so demanding"
marked by courage and determination in the face of difficulties or danger; robust and uninhibited; "you have to admire her; it was a gutsy thing to do"; "the gutsy...intensity of her musical involvement"-Judith Crist; "a gutsy red wine"
deep and harsh sounding as if from shouting or illness or emotion; "gruff voices"; "the dog's gruff barking"; "hoarse cries"; "makes all the instruments sound powerful but husky"- Virgil Thomson
inspiring fear; "the formidable prospect of major surgery"; "a tougher and more redoubtable adversary than the heel-clicking, jackbooted fanatic"- G.H.Johnston; "something unnerving and prisonlike about high grey wall"
extremely impressive in strength or excellence; "a formidable opponent"; "the challenge was formidable"; "had a formidable array of compositions to his credit"; "the formidable army of brains at the Prime Minister's disposal"