your overall circumstances or condition in life (including everything that happens to you); "whatever my fortune may be"; "deserved a better fate"; "has a happy lot"; "the luck of the Irish"; "a victim of circumstances"; "success that was her portion"
an unpleasant or disastrous destiny; "everyone was aware of the approaching doom but was helpless to avoid it"; "that's unfortunate but it isn't the end of the world"
make certain of the failure or destruction of; "This decision will doom me to lose my position"