make (alcohol) unfit for drinking without impairing usefulness for other purposes
modify (as a native protein) especially by heat, acid, alkali, or ultraviolet radiation so that all of the original properties are removed or diminished
add nonfissionable material to (fissionable material) so as to make unsuitable for use in an atomic bomb
a political organization within the Democratic Party in New York City (late 1800's and early 1900's) seeking political control by corruption and bossism
substitute a person or thing for (another that is broken or inefficient or lost or no longer working or yielding what is expected); "He replaced the old razor blade"; "We need to replace the secretary that left a month ago"; "the insurance will replace the lost income"; "This antique vase can never be replaced"
put something back where it belongs; "replace the book on the shelf after you have finished reading it"; "please put the clean dishes back in the cabinet when you have washed them"