affect; "Fear seized the prisoners"; "The patient was seized with unbearable pains"; "He was seized with a dreadful disease"
take hold of; grab; "The sales clerk quickly seized the money on the counter"; "She clutched her purse"; "The mother seized her child by the arm"; "Birds of prey often seize small mammals"
take or capture by force; "The terrorists seized the politicians"; "The rebels threaten to seize civilian hostages"
the position of greatest importance or advancement; the leading position in any movement or field; "the Cotswolds were once at the forefront of woollen manufacturing in England"; "the idea of motion was always to the forefront of his mind and central to his philosophy"