a painful burning sensation in the chest caused by gastroesophageal reflux (backflow from the stomach irritating the esophagus); symptomatic of an ulcer or a diaphragmatic hernia or other disorder
take the place or move into the position of; "Smith replaced Miller as CEO after Miller left"; "the computer has supplanted the slide rule"; "Mary replaced Susan as the team's captain and the highest-ranked player in the school"
inside or closer to the inside of the body; "the inner ear"
located inward; "Beethoven's manuscript looks like a bloody record of a tremendous inner battle"- Leonard Bernstein; "she thinks she has no soul, no interior life, but the truth is that she has no access to it"- David Denby; "an internal sense of rightousness"- A.R.Gurney,Jr.
innermost or essential; "the inner logic of Cubism"; "the internal contradictions of the theory"; "the intimate structure of matter"
exclusive to a center; especially a center of influence; "inner regions of the organization"; "inner circles of government"
an obstruction that stands in the way (and must be removed or surmounted or circumvented)
something immaterial that stands in the way and must be circumvented or surmounted; "lack of imagination is an obstacle to one's advancement"; "the poverty of a district is an obstacle to good education"; "the filibuster was a major obstruction to the success of their plan"