be in charge of, act on, or dispose of; "I can deal with this crew of workers"; "This blender can't handle nuts"; "She managed her parents' affairs after they got too old"
(with `in') guardianship over; in divorce cases it is the right to house and care for and discipline a child; "my fate is in your hands"; "too much power in the president's hands"; "your guests are now in my custody"; "the mother was awarded custody of the children"