something that causes or entails suffering; "I cannot think it a hardship that more indulgence is allowed to men than to women"- James Boswell; "the many hardships of frontier life"
arouse hostility or indifference in where there had formerly been love, affection, or friendliness; "She alienated her friends when she became fanatically religious"
remove from customary environment or associations; "Her busy schedule removed her from her duties as a mother"
having bones especially many or prominent bones; "a bony shad fillet"; "her bony wrist"; "bony fish"
very thin especially from disease or hunger or cold; "emaciated bony hands"; "a nightmare population of gaunt men and skeletal boys"; "eyes were haggard and cavernous"; "small pinched faces"; "kept life in his wasted frame only by grim concentration"