arouse hostility or indifference in where there had formerly been love, affection, or friendliness; "She alienated her friends when she became fanatically religious"
remove from customary environment or associations; "Her busy schedule removed her from her duties as a mother"
any backward region that is isolated from the world and resists progress
a body of water that was created by a flood or tide or by being held or forced back by a dam; "the bayous and backwaters are breeding grounds for mosquitos"