in a manful manner; with qualities thought to befit a man; "having said her say Peggy manfully shouldered her burden and prepared to break up yet another home"
any of various rotating shafts that serve as axes for larger rotating parts
(biology) tiny fibers that are seen in cell division; the fibers radiate from two poles and meet at the equator in the middle; "chromosomes are distributed by spindles in mitosis and meiosis"