having finished or arrived at completion; "certain to make history before he's done"; "it's a done deed"; "after the treatment, the patient is through except for follow-up"; "almost through with his studies"
make (alcohol) unfit for drinking without impairing usefulness for other purposes
modify (as a native protein) especially by heat, acid, alkali, or ultraviolet radiation so that all of the original properties are removed or diminished
add nonfissionable material to (fissionable material) so as to make unsuitable for use in an atomic bomb