place in a place where something cannot be removed or someone cannot escape; "The parents locked her daughter up for the weekend"; "She locked her jewels in the safe"
close with or as if with a tight seal; "This vacuum pack locks in the flavor!"
an unstable construction with playing cards; "he built three levels of his cardcastle before it collapsed"
a speculative scheme that depends on unstable factors that the planner cannot control; "his proposal was nothing but a house of cards"; "a real estate bubble"
charge falsely or with malicious intent; attack the good name and reputation of someone; "The journalists have defamed me!" "The article in the paper sullied my reputation"