increased pressure in the eyeball due to obstruction of the outflow of aqueous humor; damages the optic disc and impairs vision (sometimes progressing to blindness)
arouse hostility or indifference in where there had formerly been love, affection, or friendliness; "She alienated her friends when she became fanatically religious"
remove from customary environment or associations; "Her busy schedule removed her from her duties as a mother"
impervious to pleas, persuasion, requests, reason; "he is adamant in his refusal to change his mind"; "Cynthia was inexorable; she would have none of him"- W.Churchill; "an intransigent conservative opposed to every liberal tendency"