the act of constructing something (as a piece of machinery)
the act of making something (a product) from raw materials; "the synthesis and fabrication of single crystals"; "an improvement in the manufacture of explosives"; "manufacturing is vital to Great Britain"
marked by qualities giving the power to produce an intended effect; "written propaganda is less efficacious than the habits and prejudices...of the readers"-Aldous Huxley; "the medicine is efficacious in stopping a cough"