an unpleasant or disastrous destiny; "everyone was aware of the approaching doom but was helpless to avoid it"; "that's unfortunate but it isn't the end of the world"
make certain of the failure or destruction of; "This decision will doom me to lose my position"
the quality of being difficult; "they agreed about the difficulty of the climb"
a factor causing trouble in achieving a positive result or tending to produce a negative result; "serious difficulties were encountered in obtaining a pure reagent"
a condition or state of affairs almost beyond one's ability to deal with and requiring great effort to bear or overcome; "grappling with financial difficulties"