place in a place where something cannot be removed or someone cannot escape; "The parents locked her daughter up for the weekend"; "She locked her jewels in the safe"
close with or as if with a tight seal; "This vacuum pack locks in the flavor!"
be in charge of, act on, or dispose of; "I can deal with this crew of workers"; "This blender can't handle nuts"; "She managed her parents' affairs after they got too old"
making an additional point; anyway; "I don't want to go to a restaurant; besides, we can't afford it"; "she couldn't shelter behind him all the time and in any case he wasn't always with her"
despite anything to the contrary (usually following a concession); "although I'm a little afraid, however I'd like to try it"; "while we disliked each other, nevertheless we agreed"; "he was a stern yet fair master"; "granted that it is dangerous, all the same I still want to go"
in whatever way or manner; "Victory, however it was brought about, was sweet"; "however he did it, it was very clever"
to whatever degree or extent; "The results, however general, are important"; "they have begun, however reluctantly, to acknowledge the legitimacy of some of the opposition's concerns"
by contrast; on the other hand; "the first part was easy; the second, however, took hours"