treat manually, as with massage, for therapeutic purposed
hold something in one's hands and move it
control (others or oneself) or influence skillfully, usually to one's advantage; "She manipulates her boss"; "She is a very controlling mother and doesn't let her children grow up"; "The teacher knew how to keep the class in line"; "she keeps in line"
influence or control shrewdly or deviously; "He manipulated public opinion in his favor"
bring into being; "He initiated a new program"; "Start a foundation"
come into existence; take on form or shape; "A new religious movement originated in that country"; "a love that sprang up from friendship"; "the idea for the book grew out of a short story"; "An interesting phenomenon uprose"
begin a trip at a certain point, as of a plane, train, bus, etc.; "The flight originates in Calcutta"