an unpleasant or disastrous destiny; "everyone was aware of the approaching doom but was helpless to avoid it"; "that's unfortunate but it isn't the end of the world"
make certain of the failure or destruction of; "This decision will doom me to lose my position"
gradually deprive (infants and young mammals) of mother's milk; "she weaned her baby when he was 3 months old and started him on powdered milk"; "The kitten was weaned and fed by its owner with a bottle"